EDUCATION

  • Ph.D (Studying) Molecular medicine, Sun Yat-sen University, 2020.09 ~ 2023.06
  • MA.Sc Molecular medicine, Sun Yat-sen University, 2017.09 ~ 2020.06
  • B.E.Biomedical engineering, Hunan University, 2013.09 ~ 2017.06

RESEARCH INTEREST

  • 1. Predicting algorithms and tools
  • 2. Multi-omics analysis of cancer

ACADEMIC EXPERIENCE

ACADEMIC SERVICES

PUBLICATIONS

  • SCI Journals#: (Co-)first author; *: (Co-)corresponding author
  • [28] Yu K.#, Liu ZK.#, Cheng HY.#, Li SH., Zhang QF., Liu J., Ju HQ., Zuo ZX., Zhao Q., Kang SY.*, Liu ZX.* (2022) dSCOPE: a software to detect sequences critical for liquid-liquid phase separation. Briefings in Bioinformatics, Accepted. (PMID: ***)
  • [27] Yu K.#, Wang Y.#, Zheng YQ.#, Liu ZK.#, Zhang QF., Wang SY., Zhao Q., Zhang XL., Li XX., Xu RH.*, Liu ZX.* (2022) qPTM: an updated database for PTM dynamics in human, mouse, rat and yeast. Nucleic Acids Research, doi: 10.1093/nar/gkac820. (PMID: 36165955)
  • [26] Wang YN.#, Ruan DY.#, Wang ZX.#, Yu K.#, Rong DL., Liu ZX., Wang F., Hu JJ., Jin Y., Wu QN., Pu HY., Wang M., Xu RH..*, Zeng ZL.* (2022) Targeting the cholesterol-RORα/γ axis inhibits colorectal cancer progression through degrading c-myc. Oncogene, doi: 10.1038/s41388-022-02515-3. (PMID: 36316442)
  • [25] Meng Q., Lu YX., Wei C., Wang ZX., Lin JF., Liao K., Luo XJ., Yu K., Han Y., Li JJ., Tan YT., Li H., Zeng ZL., Li B., Xu RH., Ju HQ (2022) Arginine methylation of MTHFD1 by PRMT5 enhances anoikis resistance and cancer metastasis. Oncogene, 41(32):3912-3924. (PMID: 35798877)
  • [24] Zheng YQ.#, Ye YZ.#, Chen JY.#, Wei ZH.#, Liu ZK.*, Yu K.*, Zhang XP.* (2022) Prevalence and outcomes of transurethral resection versus radical cystectomy for muscle-infiltrating bladder cancer in the United States: A population-based cohort study. International Journal of Surgery, 103:106693. (PMID: 35690361)
  • [23] Chen LZ.#, Zheng YQ.#, Yu K.#, Chen SZ.#, Wang WD., Gale R., Liu ZX.*, Liang Y.* (2022) Changing causes of death in persons with haematologic cancers 1975-2016. Leukemia, DOI:10.1038/s41375-022-01596-z. (PMID: 35577905)
  • [22] Zheng YQ.#, Yang PC.#, Chen JY.#, Yu K.#, Ye YZ., Zhang L.*, Hou XH.*, Wang DS.* (2022) Endoscopic excision as a viable alternative to major resection for early duodenal cancers: A population-based cohort study. International Journal of Surgery, 101:106644. (PMID: 35500880)
  • [21] Zhang XL., Qian ZK., Wang Y., Zhang QF., Yu K., Zheng YQ., Liu ZK., Zhao Q., Liu ZX. (2022) DrugCVar: a platform for evidence-based drug annotation for genetic variants in cancer. Bioinformatics, btac273. (PMID: 35426945)
  • [20] Lin JF., Hu PS., Wang YY., Tan YT., Yu K., Liao K., Wu QN., Li T., Meng Q., Lin JZ., Liu ZX., Pu HY., Ju HQ., Xu RH., Qiu MZ. (2022) Phosphorylated NFS1 weakens oxaliplatin-based chemosensitivity of colorectal cancer by preventing PANoptosis. Signal Transduction and Targeted Therapy, 7(1):54. (PMID: 35221331)
  • [19] Ruan DY., Li T., Wang YN., Meng Q., Li Y., Yu K., Wang M., Lin JF., Luo LZ., Wang DS., Lin JZ., Bai L., Liu ZX., Zhao Q., Wu XY., Ju HQ., Xu RH. (2021) FTO downregulation mediated by hypoxia facilitates colorectal cancer metastasis. Oncogene, 40(33):5168-5181. (PMID: 34218271)
  • [18] Lin M., Zhang XL., You R., Yang Q., Zou X., Yu K., Liu YP., Zou RH., Hua YJ., Huang PY., Wang J., Zhao Q., Jiang XB., Tang J., Gu YK., Yu T., He GP., Xie YL., Wang ZQ., Liu T., Chen SY., Zuo ZX., Chen MY. (2021) Neoantigen landscape in metastatic nasopharyngeal carcinoma. Theranostics, 11(13):6427-6444. (PMID: 33995666)
  • [17] Meng Q., Lu YX., Ruan DY., Yu K., Chen YX., Xiao M., Wang Y., Liu ZX., Xu RH., Ju HQ., Qiu MZ. (2021) DNA methylation regulator-mediated modification patterns and tumor microenvironment characterization in gastric cancer. Molecular Therapy - Nucleic Acids, doi:10.1016/j.omtn.2021.03.023. (PMID: 33996253)
  • [16] Zeng ZL., Lu JH., Wang Y., Sheng H., Wang YN., Chen ZH., Wu QN., Zheng JB., Chen YX., Yang DD., Yu K., Mo HY., Hu JJ., Hu PS., Liu ZX., Ju HQ., Xu RH. (2021) The lncRNA XIST/miR-125b-2-3p axis modulates cell proliferation and chemotherapeutic sensitivity via targeting Wee1 in colorectal cancer. Cancer Medicine, 10(7):2423-2441. (PMID: 33666372)
  • [15] Li SH.#, Yu K.#, Wu GD.#, Zhang QF., Wang PQ., Zheng J., Liu ZX., Wang JC.*, Gao XJ.*, Cheng H.* (2021) pCysMod: Prediction of multiple cysteine modifications based on deep learning framework. Frontiers in Cell and Developmental Biology, 9:617366. (PMID: 33732693)
  • [14] Zhang QF.#, Yu K.#, Li SH.#, Zhang XL., Zhao Q., Zhao X., Liu ZK., Cheng H.*, Liu ZX.*, Li XX.* (2021) gutMEGA: a database of the human gut metagenome atlas. Briefings in Bioinformatics, bbaa082. (PMID: 32496513)
  • [13] Liu ZK., Zhao Q., Zuo ZX., Yuan SQ., Yu K., Zhang QF., Zhang XL., Sheng H., Ju HQ., Cheng H., Wang F., Xu RH., Liu ZX. (2020) Systematic analysis of the aberrances and functional implications of ferroptosis in cancer. iScience, 23(7):101302. (PMID: 32629423)
  • [12] Tang XW.#, Xiao Q.#, Yu K.# (2020) Breast cancer candidate gene detection through integration of subcellular localization data with protein-protein interaction networks. IEEE Transactions on NanoBioscience, 19(3):556-561. (PMID: 32340955)
  • [11] Zheng SQ., Zou YT., Xie XH., Liang JY., Yang AL., Yu K., Wang J., Tang HL., Xie XM. (2020) Development and Validation of a Stromal Immune Phenotype Classifier for Predicting Immune Activity and Prognosis in Triple-Negative Breast Cancer. International Journal of Cancer, 147(2):542-553. (PMID: 32285442)
  • [10] Li SH.#, Yu K.#, Wangd DW.#, Zhang QF, Liu ZX, Zhao LH.*, Cheng H.* (2020) Deep learning based prediction of species-specific protein S-glutathionylation sites. Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 1868(7):140422. (PMID: 32234550)
  • [9] Yang DD.#, Chen ZH.#, Yu K.#, Lu JH, Wu QN, Wang Y, Ju HQ, Xu RH, Liu ZX.*, Zeng ZL.* (2020) METTL3 promotes the progression of gastric cancer via MYC target. Frontiers in Oncology, 10:115. (PMID: 32175271)
  • [8] Yu K.#, Zhang QF.#, Liu ZK.#, Du YM.#, Gao XJ., Zhao Q., Cheng H.*, Li XX.*, Liu ZX.* (2020) Deep learning based prediction of reversible HAT/HDAC-specific lysine acetylation. Briefings in Bioinformatics, 21(5):1798-1805. (PMID: 32978618)
  • [7] Liu ZX.#, Yu K.#, Dong JS.#, Zhao LH.#, Liu ZK., Zhang QF., Li SH., Du YM., Cheng H.* (2019) Precise prediction of calpain cleavage sites and their aberrance caused by mutations in cancer. Frontiers in Genetics, 10:715. (PMID: 31440276)
  • [6] Liu ZK.#, Yu K.#, Zheng J.#, Lin H.#, Zhao Q.#, Zhang XL., Feng WY., Wang LY., Xu JJ., Xie DW., Zuo ZX.*, Liu ZX.*, Zheng QC.* (2019) Dysregulation, functional implications and prognostic ability of the circadian clock across cancers. Cancer Medicine, 8(4):1710-1720. (PMID: 30791227)
  • [5] Yu K.#, Zhang QF.#, Liu ZK.#, Zhao Q.#, Zhang XL., Wang Y., Wang ZX., Jin Y., Li XX., Liu ZX.*, Xu RH.* (2019) qPhos: a database of protein phosphorylation dynamics in humans. Nucleic Acids Research, 47:D451-D458. (PMID: 30380102)
  • [4] Zhang QB.#,*, Yu K.#, Liu ZK.#, Wang DW.#, Zhao YY., Yin. SJ, Liu ZX.* (2018) Prediction of prkC-mediated protein serine/threonine phosphorylation sites for bacteria. PLoS One, 13(10):e0203840. (PMID: 30278050)
  • [3] Wang YN., Zeng ZL., Lu JH., Wang Y., Liu ZX., He MM., Zhao Q., Wang ZX., Li T., Lu YX., Wu QN., Yu K., Wang F., Pu HY.,Li B., Jia WH., Shi M., Xie D., Kang TB., Huang P., Ju HQ., Xu RH. (2018) CPT1A-mediated fatty acid oxidation promotes colorectal cancer cell metastasis by inhibiting anoikis. Oncogene, 37(46):6025-6040. (PMID: 29995871)
  • [2] Zhao Q., Sun Y., Wang DW., Zhang HW., Yu K., Zheng J., Zuo ZX. (2018) LncPipe: A Nextflow-based pipeline for identification and analysis of long non-coding RNAs from RNA-Seq data. Journal of genetics and genomics, 45(7), 399. (PMID: 30055874)
  • [1] Liu ZK., Zhang QB., Bu C., Wang DW., Yu K., Gan ZX., Chang JF., Cheng ZY., Liu ZX. (2018) Quantitative dynamics of proteome, acetylome and succinylome during stem cells differentiation into hepatocyte-like cells. Journal of Proteome Research, 17(7):2491-2498. (PMID: 29882676)

HONORS AND AWARDS

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